MLCK inhibitor peptide 18

CAS No. 224579-74-2

MLCK inhibitor peptide 18( —— )

Catalog No. M30641 CAS No. 224579-74-2

Selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 157 Get Quote
10MG 284 Get Quote
25MG 633 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote

Biological Information

  • Product Name
    MLCK inhibitor peptide 18
  • Note
    Research use only, not for human use.
  • Brief Description
    Selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.
  • Description
    Selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    CaMK
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    224579-74-2
  • Formula Weight
    1324.64
  • Molecular Formula
    C60H105N23O11
  • Purity
    >98% (HPLC)
  • Solubility
    water:1 mg/mL
  • SMILES
    [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(N)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lukas et al (1999) Identification of novel classes of protein kinase inhibitors using combinatorial peptide chemistry based on functional genomics knowledge. J.Med.Chem. 42 910 PMID:
molnova catalog
related products
  • MPI-0479605

    MPI-0479605 is an ATP competitive and selective inhibitor.

  • CaM kinase II inhibi...

    Autocamtide-2-Related Inhibitory Peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin.

  • c-Kit-IN-1

    DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).